Centro di Referenza Nazionale (CRN) per l’Antibioticoresistenza

Istituto Zooprofilattico Sperimentale del Lazio e della Toscana M. Aleandri
Istituto Zooprofilattico Sperimentale del Lazio e della Toscana M. Aleandri

Public Service Activities of the National Reference Laboratory for Antimicrobial Resistance

  • The CRN-NRL is part of the DSPVA’s pool of experts on zoonoses responsible for depositing Italian data on the community database for the production of the EFSA Zoonoses Report. It is an accredited data-entry reporter for the website https://zoonoses.efsa.europa.eu/zoonoses/
    It is also responsible for providing technical comments on the data sent to the EFSA for the Annual Report, mentioned above;
  • The CRN-NRL provides expertise and advice for Italy as the EFSA expert in the Working Group on Antimicrobial Resistance within the BIOMO Unit (already Zoonoses Unit):   (http://www.efsa.europa.eu/en/panels.htm);

Over the years the CRN-NRL has contributed its own experts for the production of EFSA Reports and Technical Specifications related to study designs, methods to undertake baseline studies, monitoring harmonized systems and reporting systems, in the areas of zoonotic agents and antibiotic resistance.

The documents generated in the context of these activities are available at the following URL:






  •  The CRN-NRL provides expertise and advice to the European Commission on behalf of the DSPVA, Ministry of Health;
  • The CRN-NRL has provided expertise in meeting coordination as a delegate coordinator for Italy in the ‘Ad Hoc Intergovernmental Task Force on Antimicrobial Resistance of the Codex Alimentarius Commission’.

Since 2010, the CRN-NRL in agreement with the Health Ministry, extracts, organizes and sends documents using the new XML format, providing detailed information ‘at isolate level’ (general details of demographic origin and antibiotic susceptibility for every isolate), instead of only aggregated information.

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